Contact Information

Department of Biomedical Sciences
Charles Drew University of Medicine and Science
1731 E. 120th Street
Los Angeles, CA 90059
Tel: (323) 357 3672
Fax: (323) 563 9363
E-mail: vchaban@cdrewu.edu

Biosketch

Dr. Chaban received his Ph.D. from Bogomoletz Institute, Kiev and continued his training at Babraham Institute, Cambridge, U.K. Prior to coming to UCLA he worked at Nencki Institute in Warsaw. Dr. Chaban completed his post-doctoral training in Neuroscience at the Department of Medicine at UCLA and graduate training in Clinical Research at Charles Drew University of Medicine and Science. Currently Dr. Chaban is an Associate Professor of Medicine. He received Wood-Whellan Award from International Union of Biochemistry and Molecular Biology and Fellowships from International Science Foundation, European Science Foundation and UNESCO. He also received 2008 President's Award for Excellence in Servise to Charles Drew University and 2009 Life Sciences Institute Emerging Scientist Award. Dr. Chaban's area of expertise includes hormonal modulation of pain transmission at the level of primary afferent neurons and non-genomic effects of sex steroids.

Selected References

Micevych P, Chaban V, Ogi J., Sinchak K. Estrogen induced progesterone synthesis in hypothalamic astrocytes. Endocrinology 2007 148, 2, 782-789.

Chaban V, Christensen A, Wakamatsu M, McDonald M, Rapkin A, McDonald J, Micevych P. The same DRG neurons innervate uterus and colon in the rat. Neuroreport 2007, 18(3):209-12.

Chaban V. Visceral sensory neurons that innervate both uterus and colon express nociceptive TRPV1 and P2X3 receptors in rats. Ethnicity and Disease 2008 (18): Suppl 2, 20-24.

Li J, McDonald J, Rapkin A, Micevych P, Chaban V. Inflammation in the uterus induces pERK and Substance P activation in DRG neurons innervating both uterus and colon in rats. Journal of Neuroscience Research 2008, 86: 2746-2752

Chaban V. Estrogen modulation of visceral nociception. In: “Neuroactive Steroids in Brain Function, and Mental Health: New Perspectives for Research and Treatment” (Ritzner and Weizman- eds), Springer 2008, p. 89-102.

Chaban V, McRoberts J, Ennes H, Mayer EA. Nitric oxide syntase inhibitors enhance the mechanosensitive Ca2+ influx in cultured DRG neurons. Brain Research 2001;903:74-85.

Micevych P, Chaban V, Quesada A, Sinchak K. Estrogen modulates CCK-opioid interactions in the nervous system. Pharmacology and Toxicology 2002;91:387-397.

Chaban V, Mayer E, Ennes H, Micevych P. Estradiol inhibits ATP-induced [Ca2+]i increase in DRG neurons. Neuroscience 2003;118:941-948.

Chaban V, Li J, Ennes H, Nie J, Mayer E, McRoberts J. NMDA receptors enhance mechanical responses and voltage-dependent Ca2+ channels in rat DRG neurons through protein kinase C. Neuroscience 2004, 128, 347-357.

Chaban V and Micevych P. Estrogen receptor-a mediates estradiol attenuation of ATP-induced Ca2+ signaling in dorsal root ganglion neurons. Journal of Neuroscience Research, 2005, 81(1), 31-37.