Gautam Chaudhuri, M.D., Ph.D.

Professor, Obstetrics and Gynecology and Pharmacology, David Geffen School of Medicine at UCLA
 

Contact Information

UCLA Obstetrics and Gynecology
Box 951740, 27-117 CHS
Los Angeles, CA 90095-1740
On-campus mail: 174017
Tel: (310) 206-6575
Fax:
E-mail: gchaudhuri@mednet.ucla.edu


Biosketch

 

Gautam Chaudhuri, M.D., Ph.D., Professor and Executive Chair, Departments of
Obstetrics and Gynecology, and Professor, Department of Molecular and Medical Pharmacology Westwood Campus, Program Director, UCLA WRHR Center.
Dr. Chaudhuri completed his MBBS from Calcutta University, India and his M.D. from the All-India Institute of Medical Sciences, India. He then obtained a Ph.D. in Pharmacology from London University under the mentorship of Professor Sir John Vane, who won the Nobel Prize in Medicine or Physiology in 1982. He subsequently completed his residency in Obstetrics and Gynecology from the State University of New York at Buffalo and joined UCLA to do a fellowship in Reproductive Endocrinology and Infertility. Following completion of this, he joined the department as an Assistant Professor. Since joining UCLA, he has published extensively on the action of sex steroids and nitric oxide. He, together with Lou Ignarro, Professor of Pharmacology at UCLA and a Nobel Laureate, was a member of one of the first groups to demonstrate that endothelium-derived relaxing factor is nitric oxide. He has in the past and continues at present to be supported by the NIH in the form of two RO1 grants. He has served for 4 years as a member of the Human Embryology and Development Review Group of the NIH program project review groups and for 4 years as a member of the Maternal and Child Health Committee of the NICHD. Recently, he was appointed as a member of the Advisory Council of the NICHD.

 

Selected References

Mukherjee T, Dinh H, Chaudhuri G, Nathan L. Testosterone attenuates expression of Vascular Cell Adhesion Molecule-1 by conversion to Estradiol by Aromatase in Endothelial cells: Implications in Atherosclerosis. Proc Natl Acad Sci USA 2002;99:4055-4060.

Singh R, Pervin S, Chaudhuri G. Caspase -8 mediated BID cleavage and release of mitochondrial cytochrome c during N?- hydroxy L-arginine induced apoptosis in MDA-MB-468 cells: antagonistic effects of L-ornithine. J Biol Chem 2002;227:37630-37636.

Mukherjee TK, Nathan L, Dinh H, Reddy ST, Chaudhuri G. 17-Epiestriol, an estrogen metabolite, is more potent than Estradiol in inhibiting VCAM-1 mRNA expression. J Biol Chem 2003;278:11746-11752.