Current Clinical Research at CNS*

Clinical research is essential in advancing our understanding of biological and psychological mechanisms underlying functional GI disorders. The only way these studies can be performed is when affected patients are willing to participate in these studies. If you are interested in these studies, you can either participate in clinical trials in which the effectiveness of novel therapies on IBS symptoms is being evaluated or you can participate in research studies aimed at characterizing mechanisms underlying symptoms in IBS.

* CNS/WH was formerly known as UCLA/CURE Neuroenteric Disease Program

Clinical Trials

Outcomes Research

 


Research study for Men and Women with and without IBS
Conducted by Lin Chang, MD

Male and Female Volunteers Needed for Research … earn up to $150

Do you suffer from Abdominal Pain, or Discomfort, Constipation, Diarrhea, or both? Have you ever been told you have IBS (Irritable Bowel Syndrome)? Or, are you a healthy adult?

If so, and you are between the age of 18-55, you may qualify to participate in a research study conducted by Dr. Lin Chang. The main purpose of this study is to determine the sensitivity and response to unexpected sound and their effects on certain stress related hormones in IBS, and normal healthy subjects. Eligible participants will get a free medical evaluation for IBS. Compensation up to $150.00

If interested, please call (310) 206-1719

The title of the study is Startle Study.

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Men and Women with Irritable Bowel Syndrome (IBS) Needed for Research
Conducted by Lin Chang, MD

Earn up to $50 Do you suffer from Abdominal Pain, Constipation, Diarrhea, or both? Have you ever been told you have IBS?

If so, and you are between the age of 18-70, you may qualify to participate in a research study conducted by Dr. Lin Chang. The purpose of this study is to develop a diagnosis test for IBS and/or other gastrointestinal diseases. The study involves:

  • Filling out questionnaires
  • history and physical
  • 1 blood draw

Eligible participants will be compensated to $50.00.

If interested, please call (310) 206-1719


The title of the study is Procurement of blood samples for use in the development of a gastrointestinal disease test panel.

The sponsor for this study is Prometheus Laboratories Inc.

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Traditional Chinese Medicine Study for Women with IBS
Conducted by Bruce D. Naliboff, PhD

If you are female with Irritable Bowel Syndrome (IBS) and between the ages of 18 to 65 you may be eligible to participate in a study conducted by Bruce Naliboff, PhD, at UCLA Center for Neurovisceral Sciences and Women’s Health.

This research study will use Traditional Chinese Medicine approaches to compare stress responses in female IBS subjects.

Study participants will receive compensation and the following:
Study-Related Testing
Medical Examinations
Financial reimbursement for participation

Please call (310) 825-6475 for additional information or to complete a 5-10 minute telephone screening interview.

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Meditation study for Healthy Women
Conducted by Bruce Naliboff, PhD

Are you interested and committed to learning how to meditate?

Healthy women, ages 18-60, are invited to participate in a research study conducted by Brandall Suyenobu, PhD at the UCLA Center for Neurovisceral Sciences & Women’s Health.

 This study will look at the effects of mindfulness meditation on brain and stress responses using Magnetic Resonance Imaging (MRI).  Mindfulness meditation is practicing to experience being in the present moment.

Participation in the study involves:
One 8 week mindfulness meditation class
One MRI (Magnetic Resonance Imaging)
Two Pain testing procedures involving skin stimulation with heat 

You must be right-handed, not pregnant and have no recent meditation practice in order to participate.

Qualified volunteers will be compensated up to $90 and a free 8 week meditation class. For further details, please call Suzanne at (310) 478-3711 x44977

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Clinical Drug Trial with MRI for Healthy and IBS Women
Conducted by Emeran Mayer, MD

Females between the ages of 18 - 65 and either:
1) Have Irritable Bowel Syndrome (IBS) or
2) Are a healthy adult
are needed to participate in a research study conducted by Dr. Emeran Mayer at UCLA Center for Neurovisceral Sciences & Women’s Health (www.uclacns.org).
 
The purpose of this research study is to determine the effect of a new experimental drug on the brain’s response to various tasks using MRI. This drug is being evaluated for the treatment of conditions such as IBS, anxiety and other dysfunctions.

All research subjects will compensated up to $1050 for your time.

Please call (310) 268-3432 for additional information or to complete a 10-15 minute telephone screening interview.

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Mind-Body Treatment for IBS
Conducted by Bruce Naliboff, PhD

Evaluating the effectiveness of a new mind-body treatment in behavioral medicine for reducing symptoms in Irritable Bowel Syndrome. After a medical history and physical screening by a UCLA gastroenterologist, individuals accepted into the study receive one of three 10-week non-drug treatment for reducing abdominal pain and distress. Treatments include education, symptom management, stress management, cognitive-behavioral treatment, and skills training.

Enrollment: Currently open to male and female adults, ages 18 to 65 suffering from irritable bowel syndrome.

For more information, please call: (310) 478-3711 x43470

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Mind-Body Treatment with fMRI for IBS
Principal Investigator, Bruce Naliboff, PhD

Do you suffer from abdominal pain/discomfort, diarrhea or constipation? Would you like to help evaluate the usefulness of behavioral therapy in managing irritable bowel syndrome (IBS)?

If you are between the ages of 18 -55 you may be interested in participating in a randomized 6-month research study conducted by Bruce Naliboff, PhD at UCLA Center for Neurovisceral Sciences & Women's Health (www.uclacns.org).

This research study will compare the effects of behavioral therapy, such as relaxation training, to an educational program on IBS symptoms. You will have a 33% chance of being randomly selected to attend one of 3 groups. In addition, this research study will look at the differences in the brain's response to rectal sensations using a non-diagnostic fMRI brain scanning technique.

All research subjects will receive the following:

  • Medical Examinations
  • Compensation


Please call (310) 478-3711 x43470 for additional information or to complete a 10-15 minute telephone screening interview.

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We are inviting people with fibromyalgia, IBS, interstitial cystitis, chronic pain, and other chronic and recurring conditions to sign up and participate in a year-long Internet-based survey, called PROCAIM.

PROCAIM was developed under a grant from the National Center for Complementary and Alternative Medicine to UCLA researchers

  • to study the effectiveness of complementary and alternative therapies,
  • and the interactions among stress and coping, pain, and treatment outcomes

This is a web-based study composed of surveys that will recur at intervals over 1 year!

To enroll:

Log in to our web site: http://www.procaim.org.
Register as a New User.
Select clinic name: Integrative Medicine, or Mindfulness Program
Read and sign the Consent Form.

After you "sign" the form with your email address, you can begin to answer the first in a series of questionnaires. The system will send you email reminders at the time of each scheduled follow-up for one year.

For further information about PROCAIM, please contact:
Deborah Ackerman, Ph.D.
Department of Epidemiology
UCLA School of Public Health
Deborah.Ackerman@ucla.edu

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